{ "data": { "asOf": "2026-10-30T22:24:36.262Z", "dedupMethod": "exact cross-registry identifier matching; probabilistic = review only", "byRegistry": { "clinicaltrials_gov": 1 }, "canonicalTrial": { "canonicalId": "NCT07896512", "title": "Ultraformer MPT Combined With Fractional CO2 Versus Fractional CO2 Alone for Facial Rejuvenation", "scientificTitle": "A Prospective, Randomized, Hemiface-Controlled Pilot Study Evaluating Ultraformer MPT Combined With Fractional CO2 Versus Fractional CO2 Alone for Facial Rejuvenation, With Delayed Crossover", "status": "recruiting", "studyType": "interventional", "phase": [], "conditions": [ "Skin Aging" ], "interventions": [ { "name": "Ultraformer MPT", "type": "DEVICE", "description": "Micro-focused ultrasound (Classys Inc.), single session using the 1.5 mm and 2.0 mm cartridges only. Delivered to the combination hemiface at the treatment visit and to the control hemiface at Month 3." }, { "name": "SmartXide Tetra Pro fractional CO2 laser", "type": "DEVICE", "description": "Fractional ablative CO2 laser resurfacing (DEKA M.E.L.A. S.r.l.), single full-face session at the treatment visit with identical settings on both hemifaces." } ], "sponsor": { "name": "Clinique Face MD", "type": "OTHER" }, "locations": [ { "city": "Montreal", "country": "Canada", "facility": "Clinique Face MD" } ], "outcomes": { "other": [], "primary": [ "Between-hemiface difference in change in FACE-Q Satisfaction with Skin score" ], "secondary": [ "Between-hemiface difference in blinded-rater Global Aesthetic Improvement Scale (GAIS)", "Between-hemiface difference in patient-rated Global Impression of Change (PGIC)" ] }, "eligibility": { "sex": "FEMALE", "criteria": "Inclusion Criteria:\n\n1. Female, aged 50 to 65 years.\n2. Fitzpatrick skin phototype I to III on investigator clinical assessment.\n3. Mild-to-moderate facial rhytides and lower-face/jawline laxity on investigator assessment, documented on standardized baseline photographs.\n4. Stable weight (± 3 kg over the prior 6 months) with no planned major weight change.\n5. Non-smoker (no current tobacco or nicotine smoking).\n6. Able and willing to follow the pre-treatment skin-preparation, prophylaxis, and photoprotection regimen.\n7. Able and willing to attend all study visits and phone checks and comply with pre- and post-treatment care.\n8. Signed informed consent (English or French).\n\nExclusion Criteria:\n\n1. Fitzpatrick phototype IV to VI.\n2. Prior unilateral facial procedure, surgery, or trauma producing visible left-right asymmetry of the treatment zones.\n3. Thin or angular facial morphology, prior facial fat grafting, buccal fat pad excision, or visible midface/temporal hollowing at baseline.\n4. 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Any condition that, in the investigator's judgment, makes participation unsafe or data uninterpretable.", "maximumAge": "65 Years", "minimumAge": "50 Years", "healthyVolunteers": true }, "enrollment": { "type": "ESTIMATED", "count": 10 }, "startDate": "2026-10-30", "completionDate": "2027-08-31", "lastUpdated": "2026-10-27T00:00:00.000Z", "firstPosted": "2026-10-27T00:00:00.000Z", "resultsAvailable": false, "sourceRegistries": [ "clinicaltrials_gov" ], "sourceUrls": [ "https://clinicaltrials.gov/study/NCT07896512" ] }, "identifiers": [ { "idType": "nct", "idValue": "NCT07896512", "declaredBy": "clinicaltrials_gov" } ], "sourceRecords": [ { "registry": "clinicaltrials_gov", "registryName": "ClinicalTrials.gov", "license": "public-domain", "sourceId": "NCT07896512", "sourceUrl": "https://clinicaltrials.gov/study/NCT07896512", "sourceStatus": "RECRUITING", "retrievedAt": "2026-10-28T04:33:27.152Z", "payloadSha256": "d390f51603ebcb5fce9ac117419e5e0ea3f8136863d5df55c042b51488a5f212", "piiRedacted": true } ], "citation": { "canonicalId": "NCT07896512", "sources": [ { "registry": "clinicaltrials_gov", "registryName": "ClinicalTrials.gov", "license": "public-domain", "sourceId": "NCT07896512", "verifyAt": "https://clinicaltrials.gov/study/NCT07896512", "retrievedAt": "2026-10-28T04:33:27.152Z", "payloadSha256": "d390f51603ebcb5fce9ac117419e5e0ea3f8136863d5df55c042b51488a5f212", "text": "ClinicalTrials.gov, record NCT07896512 (https://clinicaltrials.gov/study/NCT07896512), retrieved 2026-10-28, licence: public-domain." } ], "crossRegistry": false, "dedupMethod": "exact cross-registry identifier matching; probabilistic = review only", "text": "Trial NCT07896512, registered in ClinicalTrials.gov, retrieved 2026-10-28. 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