{ "data": { "asOf": "2026-10-30T22:26:47.413Z", "dedupMethod": "exact cross-registry identifier matching; probabilistic = review only", "byRegistry": { "clinicaltrials_gov": 1 }, "canonicalTrial": { "canonicalId": "NCT07892651", "title": "MENA/Levant Epidemiological, Registry of Immunological & Clinical Traits (MERIT)", "scientificTitle": "A Multicenter Observational Registry of Clinical, Biological, Immunological Profiles in Underrepresented MENA/Levant With Chronic Conditions and Healthy Volunteers", "status": "not_yet_recruiting", "studyType": "observational", "phase": [], "conditions": [ "Antiphospholipid (aPL)-Positive", "Rheumatic Arthritis", "Celiac Disease", "Focal Segmental Glomerulosclerosis (FSGS)", "Membranous Nephropathy", "Crohn Disease (CD)", "Type 1 Diabetes Mellitus", "Alport Syndrome", "Pompe Disease", "Alzheimer s Disease", "Urea Cycle Disorder", "System Lupus Erythematosus", "Hyperlipidemia", "Inherited Thrombophilia", "Sickle Cell Disease (SCD)", "Parkinson Disease (PD)" ], "interventions": [], "sponsor": { "name": "Axiom Bioregistry", "type": "INDUSTRY" }, "locations": [ { "city": "Amman", "country": "Jordan", "facility": "Biosenses" } ], "outcomes": { "other": [ "Demographic and Anthropometric Characteristics of the Enrolled Population", "Geographic Distribution of the Enrolled Population" ], "primary": [ "Distribution of Enrolled Participants by Clinical Condition" ], "secondary": [] }, "eligibility": { "sex": "ALL", "criteria": "Inclusion Criteria:\n\n* Individuals of Middle Eastern, North African, or Levantine ancestry, as determined by participant self-report.\n* Individuals aged 18 years or older with chronic medical conditions; a confirmed diagnosis or self-reported history of one or more chronic medical conditions, supported by medical record review where available.\n* Individuals below 18 years of age with a relevant chronic condition, where pediatric enrollment is subject to applicable ethical approvals and the required parental or legally authorized representative permission and participant assent, as applicable.\n* Healthy volunteers: Individuals aged 18 years or older without known chronic medical conditions relevant to the registry, based on participant self-report and investigator assessment.\n* Willing and able to provide written informed consent before initiation of any study procedures or, for pediatric participants, participation will be subject to applicable written parental/legal guardian permission and assent procedures, as appropriate.\n* Eligible and willing to undergo the applicable study procedures, including collection of relevant clinical information and biological samples.\n\nExclusion Criteria:\n\n* Inability to obtain the required informed consent, parental or legally authorized representative permission, or participant assent, as applicable.\n* Acute illness, including fever (≥38°C), active infection, or a clinically unstable condition at the time of enrollment that, in the opinion of the investigator, may compromise participant safety or interfere with study procedures. 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