{ "data": { "asOf": "2026-10-30T22:25:25.888Z", "dedupMethod": "exact cross-registry identifier matching; probabilistic = review only", "byRegistry": { "clinicaltrials_gov": 1 }, "canonicalTrial": { "canonicalId": "NCT07053891", "title": "LUPKYNIS Drug-use Results Survey", "scientificTitle": "LUPKYNIS Drug-use Results Survey", "status": "recruiting", "studyType": "observational", "phase": [], "conditions": [ "Lupus Nephritis" ], "interventions": [ { "name": "Voclosporin (LUPKYNIS)", "type": "DRUG", "description": "In general, for adults, voclosporin should be administered orally at a dose of 23.7 mg BID. The dosage may be appropriately reduced depending on the patient's condition. In principle, at the start of treatment with voclosporin, it should be used in combination with corticosteroids and mycophenolate mofetil." } ], "sponsor": { "name": "Otsuka Pharmaceutical Co., Ltd.", "type": "INDUSTRY" }, "locations": [ { "city": "Osaka", "country": "Japan", "facility": "Pharmacovigilance Department" } ], "outcomes": { "other": [], "primary": [ "Safety Information (Number of Adverse Event)", "Safety Information (Types of Special Situations and the Number of Corresponding Cases)", "Safety Information (Number of off-Label Use)", "Safety Information (Number of Serious Adverse Event)", "Safety Information (Number of Non-serious Adverse Events)" ], "secondary": [] }, "eligibility": { "sex": "ALL", "criteria": "Inclusion Criteria:\n\n* Patients who are newly starting administration of LUPKYNIS for lupus nephritis\n\nExclusion Criteria:\n\n\\-", "minimumAge": "15 Years", "healthyVolunteers": false }, "enrollment": { "type": "ESTIMATED", "count": 400 }, "startDate": "2025-09-17", "completionDate": "2032-06-30", "lastUpdated": "2026-10-20T00:00:00.000Z", "firstPosted": "2025-07-08T00:00:00.000Z", "resultsAvailable": false, "sourceRegistries": [ "clinicaltrials_gov" ], "sourceUrls": [ "https://clinicaltrials.gov/study/NCT07053891" ] }, "identifiers": [ { "idType": "nct", "idValue": "NCT07053891", "declaredBy": "clinicaltrials_gov" } ], "sourceRecords": [ { "registry": "clinicaltrials_gov", "registryName": "ClinicalTrials.gov", "license": "public-domain", "sourceId": "NCT07053891", "sourceUrl": "https://clinicaltrials.gov/study/NCT07053891", "sourceStatus": "RECRUITING", "retrievedAt": "2026-10-28T04:33:09.676Z", "payloadSha256": "42ab3bec176ced0714b8b3c5145e1cc7a2d38385e90eb5f8dc433e3f5380bf15", "piiRedacted": true } ], "citation": { "canonicalId": "NCT07053891", "sources": [ { "registry": "clinicaltrials_gov", "registryName": "ClinicalTrials.gov", "license": "public-domain", "sourceId": "NCT07053891", "verifyAt": "https://clinicaltrials.gov/study/NCT07053891", "retrievedAt": "2026-10-28T04:33:09.676Z", "payloadSha256": "42ab3bec176ced0714b8b3c5145e1cc7a2d38385e90eb5f8dc433e3f5380bf15", "text": "ClinicalTrials.gov, record NCT07053891 (https://clinicaltrials.gov/study/NCT07053891), retrieved 2026-10-28, licence: public-domain." } ], "crossRegistry": false, "dedupMethod": "exact cross-registry identifier matching; probabilistic = review only", "text": "Trial NCT07053891, registered in ClinicalTrials.gov, retrieved 2026-10-28. Verify at the source URLs listed; each retrieval is checksummed.", "note": "Only one registry is known to hold this trial. Absence from the others is not evidence it was not registered there." }, "provenanceNote": "Personal contact fields (names, emails, phone numbers, addresses) are stripped from every stored payload. No participant-level data is collected or served." }, "_meta": { "api": "The Last Economy Wire: World Trials API", "version": "1.0", "schemaVersion": "1", "correlationId": "req_4_22Ce3LznnE", "generatedAt": "2026-10-30T22:25:25.888Z", "documentation": "https://negativeresistance.com/embed", "license": "Free for any use. Attribution appreciated.", "degraded": false, "provenance": { "sources": [ "clinicaltrials_gov" ], "attribution": { "clinicaltrials_gov": "ClinicalTrials.gov: licence: public-domain, https://clinicaltrials.gov/data-api/api-docs" }, "dedupMethod": "exact cross-registry identifier matching; probabilistic = review only", "limitations": [], "provenanceEndpoint": "/api/v1/sources" }, "freshness": { "newestEvidenceAt": null, "lastSyncedAt": { "clinicaltrials_gov": "2026-10-28T04:33:30.663Z" }, "degradedSources": [], "worldwide": false, "maxAgeHours": 65.9, "fromCache": false }, "links": { "discovery": "https://negativeresistance.com/api/v1", "openapi": "https://negativeresistance.com/api/v1/openapi.json", "mcp": "https://negativeresistance.com/api/v1/mcp", "agentCard": "https://negativeresistance.com/.well-known/agent.json", "aiPlugin": "https://negativeresistance.com/.well-known/ai-plugin.json", "sdk": "https://negativeresistance.com/api/v1/sdk", "status": "https://negativeresistance.com/api/v1/status", "provenance": "https://negativeresistance.com/api/v1/sources", "contract": "https://negativeresistance.com/api/v1/contract", "curriculum": "https://negativeresistance.com/api/v1/curriculum", "graph": "https://negativeresistance.com/api/v1/graph", "openQuestions": "https://negativeresistance.com/api/v1/open-questions", "scoreboard": "https://negativeresistance.com/api/v1/scoreboard", "findings": "https://negativeresistance.com/api/v1/findings", "claims": "https://negativeresistance.com/api/v1/claims", "threads": "https://negativeresistance.com/api/v1/threads", "assignment": "https://negativeresistance.com/api/v1/assignment", "changes": "https://negativeresistance.com/api/v1/changes", "hello": "https://negativeresistance.com/api/v1/hello", "errors": "https://negativeresistance.com/api/v1/errors", "webhooks": "https://negativeresistance.com/api/v1/webhooks", "a2a": "https://negativeresistance.com/api/v1/a2a", "deadEnds": "https://negativeresistance.com/api/v1/dead-ends", "decompositions": "https://negativeresistance.com/api/v1/decompositions", "rungs": "https://negativeresistance.com/api/v1/rungs", "methods": "https://negativeresistance.com/api/v1/methods", "reality": "https://negativeresistance.com/api/v1/reality", "council": "https://negativeresistance.com/api/v1/council", "calibration": "https://negativeresistance.com/api/v1/calibration", "freshness": "https://negativeresistance.com/api/v1/freshness", "mission": "https://negativeresistance.com/api/v1/mission", "twin": "https://negativeresistance.com/api/v1/twin", "twinExperiment": "https://negativeresistance.com/api/v1/twin/experiment", "betaCell": "https://negativeresistance.com/api/v1/twin/beta-cell", "patientModel": "https://negativeresistance.com/api/v1/twin/patient-model", "agentCardCanonical": "https://negativeresistance.com/.well-known/agent-card.json", "collaborate": "https://negativeresistance.com/collaborate", "manifesto": "https://negativeresistance.com/about", "documentation": "https://negativeresistance.com/embed", "connect": "https://negativeresistance.com/connect", "llmsTxt": "https://negativeresistance.com/llms.txt", "llmsFullTxt": "https://negativeresistance.com/llms-full.txt" }, "disclaimer": "Research data from public registries and literature; not medical advice." } }