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      "canonicalId": "NCT06979336",
      "title": "A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics (PK) of RO7837195 in Participants With Moderately to Severely Active Ulcerative Colitis (UC)",
      "scientificTitle": "A Phase IIb, Multicenter, Double-blind, Placebo-controlled Induction Study With an Active Treatment Extension to Assess the Efficacy, Safety, and Pharmacokinetics of RO7837195 in Patients With Moderately to Severely Active Ulcerative Colitis",
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          "name": "RO7837195",
          "type": "DRUG",
          "description": "RO7837195 will be administered as per the schedule specified in the protocol."
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        {
          "name": "RO7837195 Matched Placebo",
          "type": "DRUG",
          "description": "RO7837195 matched placebo will be administered as per the schedule specified in the protocol."
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      "sponsor": {
        "name": "Genentech, Inc.",
        "type": "INDUSTRY"
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      "locations": [
        {
          "city": "Lancaster",
          "country": "United States",
          "facility": "Gastro Care Institute"
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          "country": "United States",
          "facility": "Medical Associates Research Group, Inc."
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          "facility": "Peak Gastroenterology Associates"
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          "facility": "Clinical Research of Osceola, LLC"
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          "facility": "University of Chicago Medical Center"
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          "facility": "Intercity Gastroenterology"
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          "facility": "University of Rochester - PARENT"
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          "facility": "Monroe Biomedical Research"
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          "country": "United States",
          "facility": "University of Utah Hospitals & Clinics"
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          "country": "Australia",
          "facility": "Royal Prince Alfred Hospital"
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          "city": "South Brisbane",
          "country": "Australia",
          "facility": "Mater Misericordiae Limited"
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          "city": "Parkville VIC",
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          "facility": "Royal Melbourne Hospital"
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          "city": "Murdoch",
          "country": "Australia",
          "facility": "Fiona Stanley Hospital"
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          "city": "Fortaleza",
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          "facility": "HUWC - UFC - Hospital Universitrio Walter Cantdio - Universidade Federal do Cear"
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          "city": "Brasília",
          "country": "Brazil",
          "facility": "L2IP ?Instituto de Pesquisas Clínicas Ltda."
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          "city": "Brasília",
          "country": "Brazil",
          "facility": "Chronos Pesquisa Clinica"
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          "city": "Belo Horizonte",
          "country": "Brazil",
          "facility": "Hospital Felicio Rocho"
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          "city": "Curitiba",
          "country": "Brazil",
          "facility": "Associao Paranaense de Cultura APC"
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          "city": "Curitiba",
          "country": "Brazil",
          "facility": "Centro Digestivo de Curitiba"
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          "country": "Brazil",
          "facility": "Hospital de Clnicas de Porto Alegre"
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          "city": "Porto Alegre",
          "country": "Brazil",
          "facility": "Hospital Ernesto Dornelles"
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          "city": "Aracaju",
          "country": "Brazil",
          "facility": "Newdata Clinical Trials"
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          "city": "Ja",
          "country": "Brazil",
          "facility": "CECIP - Centro de Estudos Clínicos do Interior Paulista"
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          "city": "Santo André",
          "country": "Brazil",
          "facility": "Pesquisare Saude"
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          "city": "São José do Rio Preto",
          "country": "Brazil",
          "facility": "Kaiser Clinica"
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          "city": "São Paulo",
          "country": "Brazil",
          "facility": "Instituto de Assistencia Medica ao Servidor Publico Estudo Estadual"
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          "city": "São Paulo",
          "country": "Brazil",
          "facility": "BR Trials - Ensaios Clnicos e Consultoria"
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          "city": "So Paulo",
          "country": "Brazil",
          "facility": "CPQuali Pesquisa Clinica Ltda"
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          "city": "Rio de Janeiro",
          "country": "Brazil",
          "facility": "Hospital Gloria DOr - Hospitais Integrados da Gavea S/A"
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        {
          "city": "London",
          "country": "Canada",
          "facility": "London Digestive Disease Institute"
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        {
          "city": "Montreal",
          "country": "Canada",
          "facility": "Hopital Maisonneuve-Rosemont d/b/a CIUSSS de l'Est-de-l'le-de-Montral"
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        {
          "city": "Montreal",
          "country": "Canada",
          "facility": "Clinique IMD"
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        {
          "city": "Fuzhou",
          "country": "China",
          "facility": "The First Affiliated Hospital Of Fujian Medical University"
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        {
          "city": "Xiamen",
          "country": "China",
          "facility": "Zhongshan Hospital Xiamen University"
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        {
          "city": "Guangzhou",
          "country": "China",
          "facility": "The second Affiliated Hospital of Guangzhou Medical University"
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          "city": "Guangzhou",
          "country": "China",
          "facility": "The sixth affiliated hospital of Sun Yat-Sen University"
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        {
          "city": "Huizhou",
          "country": "China",
          "facility": "Huizhou Municipal Central Hospital"
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        {
          "city": "Zhengzhou",
          "country": "China",
          "facility": "The Second Affiliated Hospital of Zhengzhou University"
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        {
          "city": "Wuhan",
          "country": "China",
          "facility": "Renmin Hospital of Wuhan University"
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        {
          "city": "Changchun",
          "country": "China",
          "facility": "The First Hospital of Jilin University"
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          "city": "Binzhou",
          "country": "China",
          "facility": "Binzhou Medical university hospital"
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        {
          "city": "Chengdu",
          "country": "China",
          "facility": "Sichuan Provincial People's Hospital"
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          "city": "Ningbo",
          "country": "China",
          "facility": "The First Affiliated Hospital of Ningbo University"
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          "city": "Hangzhou",
          "country": "China",
          "facility": "Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University"
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          "city": "Olomouc",
          "country": "Czechia",
          "facility": "PreventaMed, s.r.o."
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          "facility": "CHU Clermont Ferrand - Hôpital d'Estaing"
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          "city": "Pierre-Bénite",
          "country": "France",
          "facility": "Centre hospitalier Lyon Sud"
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          "facility": "Universitaetsklinikum Frankfurt Goethe-Universitaet"
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          "facility": "Asian Institute of Gastroenterology"
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          "facility": "Kingsway Hospital"
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          "facility": "S. R. Kalla Memorial Gastro & General Hospital"
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          "country": "Italy",
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          "country": "Italy",
          "facility": "Fondazione IRCCS Policlinico San Matteo"
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          "city": "Rho",
          "country": "Italy",
          "facility": "ASST Rhodense, Rho Memorial Hospital"
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          "city": "Rozzano",
          "country": "Italy",
          "facility": "Istituto Clinico Humanitas"
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          "city": "San Donato Milanese (MI)",
          "country": "Italy",
          "facility": "I.R.C.C.S Policlinico San Donato"
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          "country": "Italy",
          "facility": "Ospedale Mauriziano Umberto I"
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          "city": "Negrar",
          "country": "Italy",
          "facility": "Ospedale Sacro Cuore Don Calabria"
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        {
          "city": "Kashiwa-shi",
          "country": "Japan",
          "facility": "Kokikai Tsujinaka Hospital Kashiwanoha"
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          "city": "Fukuoka",
          "country": "Japan",
          "facility": "Fukuoka University Hospital"
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          "city": "Fukuyama-shi",
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          "facility": "NHO Fukuyama Medical Center"
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          "country": "Mexico",
          "facility": "Centro Medico Clinico Quirurgico Especializado en Investigacion"
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          "country": "Mexico",
          "facility": "Centro Multidisciplinario para el Desarrollo Especializado de la Investigacion Clinica en Yucatan"
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          "country": "Mexico",
          "facility": "Centro de Alta Especialidad en Reumatología e Investigación del Potosí, S.C."
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          "country": "Mexico",
          "facility": "FAICIC S de R.L. de C.V"
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          "facility": "Clinsante S.C. Osrodek Badan Klinicznych"
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          "facility": "Centrum Medyczne Lukamed Joanna Luka"
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          "country": "Poland",
          "facility": "Vita Longa Sp. z o.o."
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          "facility": "MZ Badania Slowik Zymla Sp.j."
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          "city": "Poznan",
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          "facility": "NSZOZ Termedica Centrum Badan Klinicznych"
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          "city": "Poznan",
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          "city": "Skierniewice",
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          "facility": "Velocity Skierniewice Sp. z o.o"
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          "facility": "Przychodnia VISTAMED"
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          "country": "Poland",
          "facility": "ETG Zamosc"
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          "city": "Wŏnju",
          "country": "South Korea",
          "facility": "Yonsei University Wonju Severance Christian Hospital"
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          "city": "Busan",
          "country": "South Korea",
          "facility": "Inje university Haeundae Paik Hospital"
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          "city": "Daejeon",
          "country": "South Korea",
          "facility": "The Catholic University of Korea Daejeon ST. Mary?s Hospital"
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          "city": "Gwangju",
          "country": "South Korea",
          "facility": "Chosun University Hospital"
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          "city": "Seoul",
          "country": "South Korea",
          "facility": "Kangbuk Samsung Hospital"
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          "city": "Seoul",
          "country": "South Korea",
          "facility": "The Catholic University of Korea Eunpyeong St. Mary's Hospital"
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          "city": "Seoul",
          "country": "South Korea",
          "facility": "Asan Medical Center."
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          "country": "South Korea",
          "facility": "Samsung Medical Center"
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          "city": "Seoul",
          "country": "South Korea",
          "facility": "Chung-Ang University Hospital"
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      "patientModel": "https://negativeresistance.com/api/v1/twin/patient-model",
      "agentCardCanonical": "https://negativeresistance.com/.well-known/agent-card.json",
      "collaborate": "https://negativeresistance.com/collaborate",
      "manifesto": "https://negativeresistance.com/about",
      "documentation": "https://negativeresistance.com/embed",
      "connect": "https://negativeresistance.com/connect",
      "llmsTxt": "https://negativeresistance.com/llms.txt",
      "llmsFullTxt": "https://negativeresistance.com/llms-full.txt"
    },
    "disclaimer": "Research data from public registries and literature; not medical advice."
  }
}