{ "data": { "asOf": "2026-10-30T22:27:23.822Z", "dedupMethod": "exact cross-registry identifier matching; probabilistic = review only", "byRegistry": { "clinicaltrials_gov": 1 }, "canonicalTrial": { "canonicalId": "NCT06889740", "title": "Evaluate the Safety, Tolerability, and Efficacy of UthPeak NMNH (Reduced β-Nicotinamide Mononucleotide Calcium Salt) in Healthy Adult Participants", "scientificTitle": "A Prospective, Multi-center, Double-blind, Placebo-controlled, Randomized, Multiple-arm, Parallel Study to Evaluate the Safety, Tolerability, and Exploratory Efficacy of UthPeak NMNH (Reduced β-Nicotinamide Mononucleotide Calcium Salt) in Healthy Adult Participants", "status": "completed", "studyType": "interventional", "phase": [], "conditions": [ "Healthy Aging" ], "interventions": [ { "name": "NMNH-Ca", "type": "OTHER", "description": "Reduced Nicotinamide Mononucleotide Calcium salt" }, { "name": "Placebo", "type": "OTHER", "description": "Starch powder" } ], "sponsor": { "name": "EffePharm LTD", "type": "INDUSTRY" }, "locations": [ { "city": "Bengaluru", "country": "India", "facility": "Medstar Speciality Hospital" }, { "city": "Kāraikāl", "country": "India", "facility": "Vinayaka Mission's Medical College and Hospital" } ], "outcomes": { "other": [], "primary": [ "To assess NAD+ Values in blood", "Assessment of Biological Age", "Physical Performance walking test", "Change in BMI", "Quality (QoL) Questionnaire" ], "secondary": [ "Safety will be assessed based on number of adverse events", "Tolerability will be assessed based on number of subjects drop out due to treatment related adverse events" ] }, "eligibility": { "sex": "ALL", "criteria": "Inclusion Criteria:\n\n1. 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Participants having abnormal screening laboratory test values or other lab test result(s) that would preclude study participation in the judgment of the investigator.\n5. Participants with documented presence of atherosclerotic disease and/or cardiopulmonary disease.\n6. Participants with history of drug or alcohol abuse.\n7. Participants with history of unstable depression or mental illness within the last 6 months for which the investigator believes could impact the participant's ability to comply with study requirements.\n8. Participants unwilling to discontinue use of conventional multivitamin/mineral or other supplements at least two weeks prior to the start of study.\n9. Participants who are currently participating in or planning to begin a weight loss diet during the study period.\n10. Participants who chronically use over-the-counter medication which would interfere with study endpoints.\n11. Participants whose lifestyle or schedule incompatible with the study protocol.\n12. Participants with known hypersensitivity to the drug components used during the study.\n13. Female participants with positive result for urinary beta human chorionic gonadotropin or gestation period or breastfeeding.\n14. Other diseases or medications, according to the investigator, that would interfere directly in the results of the study or jeopardize the health of the participant.\n15. Currently, or within the past 30 days, enrolled in a different clinical investigation.\n16. Inability to provide a venous blood sample.\n17. Unable or unwilling to provide written informed consent for participation in study.\n18. Patients with a current diagnosis of any form of cancer within the past 5 years, regardless of disease stage or treatment status, are ineligible for participation in this clinical trial. 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