{
  "data": {
    "asOf": "2026-10-30T22:24:59.787Z",
    "dedupMethod": "exact cross-registry identifier matching; probabilistic = review only",
    "byRegistry": {
      "clinicaltrials_gov": 1
    },
    "canonicalTrial": {
      "canonicalId": "NCT04557462",
      "title": "A Rollover Extension Program (REP) to Evaluate the Long-term Safety and Tolerability of Open Label Iptacopan/LNP023 in Participants With Primary IgA Nephropathy",
      "scientificTitle": "A Multicenter Rollover Extension Program (REP) to Evaluate the Long-term Safety and Tolerability of Open Label Iptacopan in Adult Participants With Primary IgA Nephropathy Who Have Completed Study CLNP023X2203 or CLNP023A2301",
      "status": "recruiting",
      "studyType": "interventional",
      "phase": [
        "PHASE3"
      ],
      "conditions": [
        "Primary IgA Nephropathy"
      ],
      "interventions": [
        {
          "name": "LNP023",
          "type": "DRUG",
          "description": "Capsule 200 mg (b.i.d.) taken orally twice a day"
        }
      ],
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        "type": "INDUSTRY"
      },
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          "city": "Glendale",
          "country": "United States",
          "facility": "AZ Kidney Dise and Hypertension Ctr"
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          "country": "United States",
          "facility": "Kaiser Permanente"
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          "country": "United States",
          "facility": "North America Research Institute"
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          "country": "United States",
          "facility": "University of Colorado Anschutz"
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          "country": "United States",
          "facility": "Nephrology Associates PA"
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          "city": "Chubbuck",
          "country": "United States",
          "facility": "CaRe Research"
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          "city": "Hinsdale",
          "country": "United States",
          "facility": "Nep Assoc of Northern Illinois"
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          "facility": "Johns Hopkins Hospital"
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          "country": "United States",
          "facility": "Brigham and Womens Hosp Harvard Med School"
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          "facility": "Mayo Clinic Rochester"
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          "country": "United States",
          "facility": "Clin Rsrch Consult a JCCT Company"
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          "facility": "DaVita Clinical Research"
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          "country": "United States",
          "facility": "New Jersey Kidney Care"
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          "country": "United States",
          "facility": "Col Uni Med Center New York Presby"
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        {
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          "country": "United States",
          "facility": "Dallas Renal Group"
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        {
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          "city": "Shanghai",
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        {
          "city": "Montpellier",
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        {
          "city": "Paris",
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        {
          "city": "Freiburg im Breisgau",
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          "city": "Stuttgart",
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        {
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          "city": "Essen",
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        {
          "city": "Hanover",
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        {
          "city": "Heidelberg",
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        {
          "city": "Kiel",
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        {
          "city": "Magdeburg",
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          "city": "Mainz",
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          "city": "Tübingen",
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        {
          "city": "Ulm",
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          "city": "Hong Kong",
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          "city": "Pécs",
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          "city": "Bangalore",
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        {
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          "city": "Ashkelon",
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          "city": "Jerusalem",
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          "city": "Naples",
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          "city": "Kasugai",
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          "city": "Toyoake",
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        {
          "city": "Toyota",
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          "city": "Sendai",
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          "city": "Matsumoto",
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          "city": "Osaka",
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          "city": "Ōmihachiman",
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          "city": "Chiba",
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          "city": "Niigata",
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          "city": "Okayama",
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          "city": "Osaka",
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          "city": "Kuala Lumpur",
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          "city": "Benito Juárez",
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          "city": "Rostov-on-Don",
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        {
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        {
          "city": "Singapore",
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        {
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        {
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        {
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        {
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        {
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        {
          "city": "Seoul",
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        {
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        {
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        {
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        {
          "city": "Salamanca",
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          "city": "Antalya",
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        {
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        {
          "city": "Istanbul",
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        {
          "city": "Ankara",
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        {
          "city": "Mersin",
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        {
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        {
          "city": "Cambridge",
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        {
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        {
          "city": "London",
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        {
          "city": "Salford",
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        {
          "city": "Ho Chi Minh City",
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        {
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      ],
      "outcomes": {
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          "Number and percentage of participants with adverse event",
          "Number and percentage of participants with adverse events of special interest",
          "Number and percentage of participants with abnormalities in vital signs",
          "Number and percentage of participants with abnormalities in ECG",
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        "secondary": [
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          "Change from baseline in eGFR",
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